Focusing on repertoire from the 16th and early 17th centuries, the vocal ensemble Profeti della Quinta aims to create vivid and expressive performances for audiences today. In particular, this is achieved through addressing the performance practices of the time. From its core of five male singers, this a-cappella ensemble also collaborates with instrumentalists and additional singers where required.

Profeti della Quinta have been active in researching and performing hitherto neglected repertoire, such as Emilio de' Cavalieri's Lamentations (1600) and Salomone Rossi's Hashirim asher li'Shlomo (1623), the first publication of polyphony in Hebrew, which they recorded on PAN Classics to critical acclaim. The ensemble performs regularly in various festivals and venues in Europe and Israel, such as the Oude Muziek Festival in Utrecht (the Netherlands), the Festival von Vlaanderen (Belgium), and the Biennale alter Musik Berlin. Profeti della Quinta took part in a documentary about Salomone Rossi, flimed in Mantua. in July 2011 the ensemble won the York Early music young artists competition. Highlights of the 2013-2014 season include concerts in Canada, Japan, France and Sweden.